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» Cyclophosphamide 50mg (Cytoxan)
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Cyclophosphamide is a medication used to treat various types of cancer and autoimmune diseases. It is also sometimes used in stem cell transplant conditioning regimens.
Uses:
- Treatment of various types of cancer, including leukemia, lymphoma, multiple myeloma, and breast cancer.
- Treatment of autoimmune diseases, including lupus, rheumatoid arthritis, and multiple sclerosis.
- Stem cell transplant conditioning regimens.
Dosage:
- The dosage and schedule of cyclophosphamide depends on the condition being treated, the patient's age, weight, and overall health, and other factors.
- Cyclophosphamide is usually given as an infusion into a vein (intravenous) or taken orally (by mouth).
- The usual dose for adults is 1 to 5 mg/kg/day, usually for a period of 1 to 5 days, repeated every 2 to 4 weeks.
- The dose for children is based on their weight and is typically lower than for adults.
Side Effects:
- Cyclophosphamide can cause a variety of side effects, some of which may be serious or life-threatening.
- Common side effects include nausea, vomiting, diarrhea, mouth sores, hair loss, and a temporary drop in blood cell counts.
- Serious side effects may include an increased risk of infection, bleeding, kidney damage, and an increased risk of certain types of cancer, such as leukemia and bladder cancer.
- Other potential side effects include infertility, premature menopause, and an increased risk of developing secondary cancers.
Precautions:
- Cyclophosphamide should only be used under the supervision of a healthcare provider who is experienced in using this medication.
- Patients taking cyclophosphamide should have regular blood tests to monitor their blood cell counts and kidney function.
- Women who are pregnant or breastfeeding should not take cyclophosphamide.
- Patients taking cyclophosphamide should avoid live vaccines and contact with people who have recently received live vaccines, as their immune system may be weakened by the medication.
- Patients taking cyclophosphamide should take precautions to avoid infection, such as washing their hands frequently and avoiding contact with people who are sick.
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