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Zofran is a brand name for the medication Ondansetron, which is a type of medication called a serotonin receptor antagonist. It is commonly used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery.
Uses:
Zofran is primarily used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery. It is also sometimes used to treat nausea and vomiting caused by other medical conditions, such as gastroenteritis, migraine headaches, or vertigo.
Dosage:
Zofran is available in several forms, including tablets, orally disintegrating tablets, and injections. The dosage and frequency of Zofran may vary depending on the individual's condition, age, and other factors. The usual adult dose for preventing chemotherapy-induced nausea and vomiting is 8 mg taken orally 30 minutes before the start of chemotherapy, followed by 8 mg every 8 hours for up to 2 days after chemotherapy. The usual pediatric dose is based on the child's weight and is typically given as a single dose before chemotherapy.
Side effects:
Like any medication, Zofran may cause side effects. The most common side effects include headache, constipation, and diarrhea. Other potential side effects may include dizziness, fatigue, drowsiness, and blurred vision. Rarely, Zofran may cause a serious condition called serotonin syndrome, which can be life-threatening. Signs of serotonin syndrome include confusion, agitation, fever, sweating, fast heartbeat, and muscle stiffness.
Precautions:
Before taking Zofran, individuals should inform their healthcare provider if they have a history of liver disease, heart disease, or any other medical conditions. Zofran should not be taken by individuals with a known allergy to ondansetron. Zofran should also be used with caution in individuals taking other medications that affect serotonin levels, as this may increase the risk of serotonin syndrome. Finally, Zofran may cause drowsiness, so individuals should avoid driving or operating heavy machinery until they know how the medication affects them.
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